In contrast, a strong signal was apparent in the anterodorsal nucleus, which projects to limbic areas, and this persisted at P28. 
c1502/QP-C mRNA was localized at high levels in the olfactory bulb, cerebral cortex, hippocampus, thalamus (anterodorsal nucleus, parafacicularis nucleus), tegmentum (red nucleus), cerebellum (Purkinje and granule cells), and pons (pontine nucleus, reticulotegmental nucleus, trapezoid body, vestibular nucleus).
Both controls and pilocarpine-treated animals presented neo-Timm staining in the anterodorsal nucleus, laterodorsal nucleus, reticular nucleus, most intralaminar nuclei, nucleus reuniens, and rhomboid nucleus of the thalamus, as well as in the zona incerta.
Congruent distribution patterns of Tac2 mRNA and NKB were found in many nuclei of the thalamus and hypothalamus (habenula, anterodorsal nucleus, preoptic area, arcuate nucleus, paraventricular nucleus).
In the thalamus, positively labeled neurons were detected in the reticular nucleus with ERG1 and ERG3 and in the anterodorsal nucleus with ERG2 riboprobes.
Thalamic projections from Rgb target the anteroventral and laterodorsal nuclei of the thalamus, with only a few axons terminating in the anterodorsal nucleus, the reticular nucleus, and the nucleus reuniens of the thalamus.
Unexpectedly, we found robust Narp expression in several discrete areas linked to the vestibular system: the anterodorsal nucleus (ADN) of the thalamus, which relays head orientation information to the cortex, the lateral vestibulospinal (Deiters') nucleus and Purkinje cells in the flocculonodular lobe of the cerebellum.
In the accompanying study, we have identified a 5-HT7 receptor-mediated depolarization in the anterodorsal nucleus of the thalamus (ADn).
Therefore, we used whole-cell recording techniques in the in vitro brain slices to examine the effects of serotonin on neurons of the anterodorsal nucleus of the thalamus (ADn).
There were no differences between strains in specific IMEL binding in the medial PVNt, anteroventral and anterodorsal nucleus of the thalamus, suprachiasmatic nucleus, or the pars tuberalis.
In detail, angiotensin II binding sites were found in the anterodorsal nucleus, in the laterodorsal and posterior nucleus of the thalamus, as well as in the lateral geniculate nucleus, the reticular thalamic nucleus and in the zona incerta..
The density of binding sites was high in the islands of Calleja, accumbens nucleus, caudate putamen and olfactory tubercles, moderate in the hippocampus, amygdala and anterodorsal nucleus of the thalamus.
In the thalamus, novel sites of expression included the anterodorsal nucleus, lateral habenula, and zona incerta, where labeling was much more extensive than previously reported.
All the areas of the retrosplenial cortex provide sparse projections, mainly ipsilateral, to the anterodorsal nucleus, with a crude topographic pattern such that the rostrocaudal axis of the retrosplenial cortex corresponds to the caudorostral axis of the anterodorsal nucleus.
At E17 strong NOS-LI was observed in the developing neurons of the hypothalamic paraventricular nucleus, supraoptic nucleus, anterodorsal nucleus and lateral hypothalamic areas.
Thus, the highest levels of immunostaining were observed in the islands of Calleja, diagonal band of Broca, magnocellular preoptic nucleus, pre- and parasubiculum, suprachiasmatic nucleus, anterodorsal nucleus of the thalamus, substantia nigra, ventral tegmental area, pontine nuclei and dorsal motor nucleus of the vagus, all of which had previously been documented to contain high densities of neurotensin binding sites.
In the thalamus, the habenula, anterodorsal nucleus and medial geniculate body, together with the paraventricular hypothalamic nuclei, had prominent reactive neuronal somata and dendrites in the neuropil.
The ventral nucleus has a high density of parvalbumin cells and few calbindin cells, and the anterodorsal nucleus has a high density of parvalbumin cells and moderate numbers of calbindin cells.
Following injection of tracer into the dorsal part of the rostral anteroventral nucleus, retrograde labelled GABA-containing cell bodies were also found in the ipsilateral anterodorsal nucleus..
Here, head-direction cells were recorded from the post-subicular cortex (PSC) and anterodorsal nucleus (ADN) of the thalamus of freely moving rats.
Axons from the anterodorsal nucleus occupied the rostralmost tip of both inner and outer zones of the dorsal limbic sector.
Following microinfusions into the subicular region, the somata of zinc-containing neurons were found in the hippocampus, the pre- and para subiculum, retrosplenial, cingulate, and perirhinal cortices, and in the anterodorsal nucleus of the thalamus.
Other major sites of PTH/PTHrP receptor expression included the anterodorsal nucleus of the thalamus, basolateral amygdala, entorhinal cortex, parasubiculum, cells in the Purkinje cell layer of the cerebellum, vestibular nuclei, ventral cochlear nucleus, the motor nucleus of the trigeminal, and the facial and external cuneate nuclei.
Here we describe a thalamo-cortical pathway that is zinc-containing, namely, the projection from the anterodorsal nucleus of the thalamus to the subicular cortex.
They are also transiently coexpressed in principal neurons of the anterodorsal nucleus, but IGF-I mRNA disappears from this structure shortly after birth, while IGFBP5 mRNA remains highly abundant here in the adult.
The anterodorsal nucleus projects mainly to deep layers of the presubiculum, parasubiculum, and entorhinal area.
For instance, mGluR1 occurs in the apparent absence of IP3R in neurons of the stratum oriens of the CA1 hippocampus, islands of Calleja, anterodorsal nucleus of thalamus, lateral nucleus of hypothalamus, and the granular cell layer and the deep nuclei of cerebellum.
The anteroventral nucleus projects to layers I and IV of the retrosplenial granular area, whereas the anterodorsal nucleus projects to layers I, III and IV of the same area.
Some intralaminar nuclei (central medial, central lateral, and paracentral), the reticular nucleus, midline nuclei (paraventricular and reuniens), some nuclei associated with the limbic system (anterodorsal nucleus and medially situated patches in the mediodorsal nucleus) and the lateral geniculate nucleus displayed the highest density of ChAT-positive axonal varicosities.
The medial mammillary nucleus (MM) projects predominantly ipsilaterally to the entire anterior thalamic nuclei, whereas the lateral mammillary nucleus projects bilaterally to the anterodorsal nucleus (AD) of the anterior thalamic nuclei.
Severe neuronal loss and tangle formation were evident in the anterodorsal nucleus from the AD cases.
Specific OXO-M/PZ binding increased in the parvocellular division of the anterodorsal nucleus early in training when the animals were first exposed to pairing of the conditional and unconditional stimuli.
The presubiculum also projects to the anteroventral and laterodorsal nuclei of the thalamus, and the lateral ventral portion of the medial mammillary nucleus, whereas the parasubiculum projects prominently to the anterodorsal nucleus of the thalamus, the contralateral presubiculum and parasubiculum, and the lateral dorsal segment of the medial mammillary nucleus.
Single-unit activity and ultrastructural characteristics were investigated in anterodorsal nucleus of thalamus (AD) in rabbits, guinea pigs and rats.
The number of neurons and neuroglia in the anterodorsal nucleus of the thalamus and in the lateral mammillary nucleus of the ASH/TO strain mouse was estimated at 6, 25, 28 and 31 months of age. There was no significant variation in neuron number in either nucleus with age but there was a statistically significant increase (approximately 20%) in the number of neuroglia in the anterodorsal nucleus between 28 and 31 months of age which raised the glia to neuron ratio from 0.59 to 0.72. This was first evident at 28 months in the anterodorsal nucleus and at 31 months in the lateral mammillary nucleus.
The anterodorsal nucleus and the anteroventral nucleus project to posterior area 24 and all of area 29.
The neurons of the anterodorsal nucleus are generated over a 3-day period between days E15-E17 and show a lateral-to-medial neurogenetic gradient.
Staining was most intense in the hypothalamic suprachiasmatic and supraoptic nuclei, as well as the anterodorsal nucleus of the thalamus, medial and lateral habenular nuclei and associated fibre tracts.
In addition, a substantial number of labeled cells were also detected in the anterior and lateral dorsal nuclei, particularly in the anterodorsal nucleus, which contained densely arranged labeled cells throughout almost the entire rostrocaudal extent.
At the level of the anterior nuclear group, GABA-positive cells and terminals abounded in the anterodorsal nucleus but were much less numerous in the anteromedial and anteroventral nuclei.
A marked discrepancy, however, was found in the anterodorsal nucleus, which was intensely stained for acetylcholinesterase but contained no apparent choline acetyltransferase immunoreactivity.
Coexistence of neuropeptides was suggested by double-staining immunohistochemistry in projection neurons in the thalamus of the cat; cholecystokinin (CCK)-like immunoreactivity (LI) and vasoactive intestinal polypeptide (VIP)-LI in the rostral group of the intralaminar nuclei, CCK-LI and neurotensin (NT)-LI in the anterodorsal nucleus and NT-LI and VIP-LI in the laterodorsal nucleus..
The most dense collection of perikarya containing CCK-IR was seen in the rostral group of the intralaminar nuclei, in rostral parts of the rhomboid nucleus and the anterodorsal nucleus.
The activity of anterodorsal nucleus neurons was represented mainly by high-frequency grouped discharges with long intergroup intervals..
All limbic cortical areas send projections bilaterally to all regions of the anteromedial nucleus as well as to the parvicellular parts of the anteroventral thalamic nucleus, while the anterodorsal nucleus receives ipsilateral projections originating exclusively from the preagranular, anterior limbic, and cingular regions. Some neurons in the infralimbic region also project bilaterally to all of the anterior thalamic nuclei except the anterodorsal nucleus.
photic and electrical stimulation of the anterodorsal nucleus (ADN).
The anterodorsal nucleus has regressed into a small, flattened cap-line structure covering the dorsal surface of the anteroventral nucleus.
The lateral mammillary nucleus projects bilaterally to the anterodorsal nucleus..
The anterodorsal nucleus projects to the retrosplenial, postsubicular and presubicular areas. The posterior portion of the retrosplenial area receives no fibers from the anterodorsal nucleus.
The ultrastructure and synaptic organization of the anterodorsal nucleus (AD) of the thalamus were investigated under normal and experimental conditions.
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